If you face a condition where in the C:\ on server 2008 x64 (in my case SCOM 2007 R2 CU5 RMS server) becomes full and you have no more space and don't know what to delete : This is what i deleted and think didn't affect my sever. Clean up Winsxs a little bit: C:\Windows\winsxs http://blogs.technet.com/b/askcore/archive/2008/09/17/what-is-the-winsxs-directory-in-windows-2008-and-windows-vista-and-why-is-it-so-large.aspx Deleted the files under C:\Windows\ServiceProfiles\LocalService\AppData\Local\Temp (5GB) -- the file modified dates were 3 years ago. So i took a chance Move the archive Security Logs to other location : C:\Windows\System32\winevt\Logs (5GB) You can run Disk Cleanup utility (however you need to Install Desktop Experience feature on the server as Disk cleanup is not part of Windows 2008 and need to be added as a feature) Uninstalled programs from the server that no longer were needed. (e.g management...