Sometime when you upgrade Citrix receiver or uninstall an older version and then install a new Citrix Receiver version , you may see an issue opening application /desktops (Citrix XenApp / XenDesktop) You may see errors as shown in the image: --------------------------- Microsoft Visual C++ Runtime Library --------------------------- Runtime Error! Program: C:\PROGRA~2\Citrix\ICACLI~1\WFICA32.EXE It may happen that an older installation of Citrix Receiver did not get cleaned up properly. Try and check if this entry exist in registry and then delete it. HKEY_CLASSES_ROOT\Installer\UpgradeCodes\9B123F490B54521479D0EDD389BCACC1 Hope this helps.